Few artists have left as profound a mark on music and culture as Tupac Shakur, better known as 2Pac. More than just a rapper, he was a poet, activist, visionary, and voice of a generation—someone whose words carried the weight of struggle, hope, love, and revolution. From the streets of Oakland to the global stage, 2Pac’s music continues to inspire, provoke, and resonate nearly three decades after his untimely death. His catalog is vast, but certain songs rise above the rest—tracks that defined his legacy, shook the industry, and captured the raw essence of who he was.
In this list, we’re diving into the Top 10 Most Popular 2Pac Songs of All Time—not just by chart performance, but by lasting impact, lyrical power, and cultural influence. Whether he was delivering a heartfelt tribute to his mother, calling out injustice, or declaring war on his rivals, every track on this list showcases a different side of 2Pac’s genius. If you’re a longtime fan or someone discovering his music for the first time, these songs are essential listening. Get ready to revisit the anthems that made 2Pac a legend—and understand why his voice still echoes louder than ever.
1. California Love (1995)
Released in December 1995, “California Love” signaled 2Pac’s powerful comeback after his prison release. Collaborating with Dr. Dre, who also produced the track, this West Coast anthem captured the essence of California’s vibrant culture. The song opens with a catchy synth line sampled from Joe Cocker’s “Woman to Woman,” paired with Dre’s signature G-funk production. Together, they created a song brimming with energy and undeniable swagger. 2Pac’s charismatic verses and Dre’s slick delivery made “California Love” an instant classic, resonating deeply with listeners across the nation. Not only did it peak at No. 1 on the Billboard Hot 100, but it also dominated radio airwaves, becoming an anthem for West Coast rap. The iconic, Mad Max-inspired music video amplified its larger-than-life status, transforming the track into a cultural moment. More than just a hit, “California Love” marked a coronation for 2Pac, cementing his place as a rap legend and setting the stage for his landmark double album All Eyez on Me.
2. Changes (1998)
Although released posthumously in 1998, “Changes” was recorded in 1992 during 2Pac’s R U Still Down? sessions. This track remains one of his most poignant reflections on race, social injustice, and the struggles of urban life. Built around a sample of Bruce Hornsby and the Range’s 1986 hit “The Way It Is,” 2Pac’s lyrics take on timeless significance, addressing police brutality, systemic inequality, and the cycle of violence that affects marginalized communities. Despite the track’s initial recording in the early ’90s, the themes in “Changes” resonate just as deeply today. The song’s blend of social commentary and melodic hooks made it commercially successful, while staying true to 2Pac’s revolutionary message. This song reached new audiences, exposing younger listeners to 2Pac’s unique ability to blend powerful messages with accessible melodies, and it remains one of his most impactful pieces of music.
3. Hit ‘Em Up (1996)
Released in June 1996 as the B-side to “How Do U Want It,” “Hit ‘Em Up” is one of the most infamous diss tracks in hip-hop history. In it, 2Pac unleashes a brutal tirade against The Notorious B.I.G., Bad Boy Records, and their associates, driven by personal betrayal and the fierce East Coast vs. West Coast rivalry. From the very first line, “That’s why I fed your b**, you fat motherf***r,” the song sets a tone of unrelenting hostility and venom. Backed by the Outlawz and a sinister beat sampled from Dennis Edwards’ “Don’t Look Any Further,” the track’s aggression and raw emotion shook the rap world. Though controversial, “Hit ‘Em Up” showcased 2Pac’s fearless personality and his unrivaled ability to command attention. It wasn’t just a diss—it was a declaration of war in the rap world, leaving an indelible mark on hip-hop history.
4. Hail Mary (1996)
“Hail Mary,” released in November 1996 under 2Pac’s Makaveli alias, stands as one of his most haunting and introspective songs. It was part of his The Don Killuminati: The 7 Day Theory album, which was completed just weeks before his tragic death. The song’s eerie, minimalist production by Hurt-M-Badd sets a somber, almost spiritual atmosphere, aligning with the darker themes of 2Pac’s lyrics. Addressing death, vengeance, and inner conflict, “Hail Mary” showcases 2Pac at his most reflective, with the verses delving into themes of fate, redemption, and despair. Unlike his more aggressive songs, this track’s slower pace and hypnotic hook evoke a sense of deep contemplation. Featuring members of the Outlawz—Kastro, Young Noble, and Yaki Kadafi—the song takes on a ritualistic, almost confessional tone. “Hail Mary” is a chilling reminder of 2Pac’s complexity as an artist, blending street realities with philosophical musings, making it one of his most significant works.
5. Keep Ya Head Up (1993)
Released in October 1993, “Keep Ya Head Up” is one of 2Pac’s most heartfelt and socially conscious tracks. Departing from the aggression of his earlier work, the song highlights 2Pac’s compassionate side as he addresses the struggles of women—particularly single mothers and victims of abuse. Built around smooth samples from Zapp’s “Be Alright” and The Five Stairsteps’ “O-o-h Child,” the track’s soulful production complements 2Pac’s message of resilience and empowerment. His lyrics challenge societal neglect, misogyny, and poverty, calling for respect and unity in the face of hardship. The chorus, “Keep ya head up,” became a powerful mantra, resonating with listeners who needed hope and strength. 2Pac’s sincerity and vulnerability on this track turned it into an anthem for empowerment, especially for women who found in him an ally in the male-dominated rap world. “Keep Ya Head Up” solidified 2Pac’s reputation as a voice for the voiceless, showing his ability to balance social commentary with uplifting messages.
6. Dear Mama (1995)
“Dear Mama,” released in February 1995, remains one of 2Pac’s most deeply personal and emotionally charged songs. A tribute to his mother, Afeni Shakur, the track honors her strength, resilience, and undying love despite the challenges they faced. Set against a warm, nostalgic beat that samples The Spinners’ “Sadie,” 2Pac reflects on his childhood struggles, from poverty to his mother’s addiction, but with a tone of gratitude and understanding rather than bitterness. The raw honesty and vulnerability in the lyrics broke new ground in hip-hop, a genre not often known for such tender displays of emotion. “Dear Mama” became more than just a hit—it became a cultural breakthrough, offering a rare and humanizing glimpse into the life of one of rap’s biggest icons. Inducted into the Library of Congress’ National Recording Registry in 2010, the song’s legacy endures as a universal ode to motherhood and resilience.
7. Ambitionz Az a Ridah (1996)
The opening track of All Eyez on Me, “Ambitionz Az a Ridah,” released in February 1996, is pure adrenaline. The moment the hypnotic piano loop kicks in, it’s clear that 2Pac is bringing his most confident, aggressive energy. Produced by Daz Dillinger, the minimalist yet menacing beat allows 2Pac’s fiery delivery to take center stage. The song introduces 2Pac as a force to be reckoned with, fresh out of prison and ready to reclaim his place at the top. His defiant lyrics, including the iconic line “I won’t deny it, I’m a straight ridah,” capture his outlaw persona and set the tone for the rest of his career. “Ambitionz Az a Ridah” became a fan favorite, thanks to its raw energy and unapologetic swagger. It’s more than just an album opener—it’s a declaration of power and independence, and it remains one of 2Pac’s most iconic tracks.
8. 2 of Amerikaz Most Wanted (1996)
Released in May 1996, “2 of Amerikaz Most Wanted” is an unforgettable collaboration between 2Pac and Snoop Dogg. The chemistry between the two West Coast legends is undeniable, as they trade verses over a funky, laid-back beat produced by Daz Dillinger. The track exudes confidence, camaraderie, and rebellion, capturing the essence of gangsta rap at the height of its popularity. 2Pac and Snoop’s playful yet assertive verses offer a carefree attitude towards their legal troubles and media scrutiny, celebrating their survival and dominance in the rap game. The accompanying music video, featuring a mock trial and daring escape, only adds to the track’s larger-than-life feel. “2 of Amerikaz Most Wanted” wasn’t just a hit—it was a moment, cementing 2Pac and Snoop as two of the most influential figures in hip-hop.
9. I Ain’t Mad at Cha (1996)
Released just days after 2Pac’s death in September 1996, “I Ain’t Mad at Cha” is a bittersweet reflection on change, growth, and the passage of time. Set to a soulful piano sample from DeBarge’s “A Dream,” the song finds 2Pac addressing friends who’ve taken different paths, some finding religion or moving away from the street life. Instead of harboring bitterness, he offers understanding and respect. The hook, sung by Danny Boy, adds a smooth, heartfelt touch, creating a mood of reflection and acceptance. The song’s music video, depicting 2Pac being shot and ascending to heaven, took on an eerie significance following his death, turning it into a poignant posthumous elegy. “I Ain’t Mad at Cha” is one of 2Pac’s most introspective tracks, showing his emotional maturity and ability to navigate personal growth even amidst chaos.
10. Brenda’s Got a Baby (1991)
Released in December 1991, “Brenda’s Got a Baby” was 2Pac’s debut single, and it immediately demonstrated his exceptional storytelling abilities. The track is inspired by the true story of a 12-year-old girl who becomes pregnant and is abandoned by society. Through vivid, compassionate lyrics, 2Pac brings attention to issues like poverty, neglect, and systemic failure that are rarely discussed in mainstream hip-hop. The somber beat sets the tone for the heartbreaking narrative, as 2Pac paints a vivid picture of Brenda’s struggles. Unlike many of his peers, 2Pac used his platform to advocate for social justice and shed light on the forgotten, showing early on that his music would be about more than just street life. While “Brenda’s Got a Baby” didn’t top the charts, it firmly established 2Pac as a rapper with a message, laying the groundwork for his career as an artist who spoke truth to power.
Samuel Moore is a frequent contributor to Singers Room. Since 2005, Singersroom has been the voice of R&B around the world. Connect with us via social media below.
